Special Issue Submission Closed

Chemical Biology

View Published Articles  →

01About This Special Issue

Chemical Biology is a research field that aims at the synthesis of biologically active molecules and the analysis of their induced phenotypes. Chemical Biology is providing new tools for deciphering protein modification and activity. Designing small molecules as probes of protein and cellular function are becoming the method of choice for careful profiling and development of biological processes in areas such as drug discovery, neurochemistry and molecular genetics. Chemical Biology studies also include aging, microfluidics, neurodegenerative diseases, human immunodeficiency virus and drug development. Chemical biology new technologies may accelerate the discovery of still elusive cures to neurodegenerative diseases. This issue is intended for more research and discussion on chemical biology and its application and benefits to human health.

02Meet the Guest Editors

Our distinguished editors bring deep subject-matter expertise to curate high-quality research and ensure a rigorous peer-review process.

Lead Guest Editor

Michael Ioelovich

Department of Biological Chemistry, Faculty of Biochemistry, Weizmann Institute of Science, Rehovot, Israel

Guest Editor

Joanna Chan

Wuhan, China, Andorra

Guest Editor

Tuhin Subhra Santra

California Nano Systems Institute, University of California at Los Angeles, Los Angeles, United States

Guest Editor

2325dasdasd 2325dasdasd

12312312, Australia

Guest Editor

Joanna Chan

Wuhan, China, Andorra

Guest Editor

Jiangsong Jiang

National Institute of Allergy and Infectious Diseases, Frederick National Laboratory for Cancer Research, National Institute of Health, United States

Guest Editor

Palanisamy Arulselvan

Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience (IBS), University Putra Malaysia, Serdang, Malaysia

Guest Editor

Jiangsong Jiang

National Institute of Allergy and Infectious Diseases, Frederick National Laboratory for Cancer Research, National Institute of Health, United States

Guest Editor

Karthik Bodhinathan

Sanford-Burnham Medical Research Institute, La Jolla, United States

Guest Editor

Manoj Kumar Upadhyay

Department of Education and Biotechnology, Biotech Park, Lucknow, India

Guest Editor

M.Prasad Naidu

Department of Biochemistry, Advance Research centre, Narayana Medical College and Hospital, Nellore, India

Guest Editor

AMIT SHARMA

Department of Physics, College of Engineering, Teerthanker Mahaveer University, Moradabad, India

Guest Editor

Saurabh Maru

Department of Pharmacy, Shri G S Institute of Technology and Science, Indore, India

Guest Editor

Atul Bhangale

Biologics Research amd Process Development, Bristol Myers Squibb, United States

Guest Editor

Andrea Greschner

Institut national de la recherche scientifique - Energie, materiaux, et telecommunications, Varennes, Canada

Guest Editor

AMIT SHARMA

Department of Physics, College of Engineering, Teerthanker Mahaveer University, Moradabad, India

Guest Editor

Emad Dwidar

Botany Department, Fayoum University, Fayoum, Egypt

Guest Editor

Niha Ansari

Gujarat University, Ahmedabad, India

Guest Editor

A.K.M. Fahmidul Haque

Respiratory and Antibiotics Laboratory, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh

Guest Editor

Zhe Wang

National Institutes of Health, United States

Guest Editor

Cunye Qu

Center for Craniofacial Molecular Biology, University of Southern California, Losangeles, United States

Guest Editor

Vishvanath Tiwari

Department of Biochemistry, Central University of Rajasthan, Ajmer, India

Guest Editor

Vishvanath Tiwari

Department of Biochemistry, Central University of Rajasthan, Ajmer, India

Guest Editor

Ozlem Alptekin

Department of Biochemistry, Cukurova University, Adana, Turkey

Guest Editor

Niha Ansari

Gujarat University, Ahmedabad, India

03Published Articles

The following articles have been published in this special issue.

  • Physico-Chemical Analysis of Waste Water Used for Agricultural Purpose in Surrounding of Hyderabad, Sindh, Pakistan

    Ghulam Murtaza Mastoi , Khalid Hussain Lashari , Zameer Ali Palh , T. Jabeen Ursani , Anila Naz Soomro , Zulfiqar Ali Laghari , Abdul Waheed Mastoi

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 39-42
    Received: 4 August 2014
    Accepted: 8 August 2014
    Published: 2 September 2014
    DOI: 10.11648/j.ajbio.s.2014020601.17
    Downloads:
    Views:
    Abstract: Irrigation with sewage is common practice of the farmers living in surrounding areas of urban colonies in Pakistan. Sewage contains a complex mixture of impurities. Waste water used for agricultural purpose without any treatment though it contains lot of the harmful impurities. During this study three villages were selected around the Hyderabad cit... Show More
  • Expression of Hox Genes, Zen (GB 51301) ANT and UBX during the Development of Honey Bee (Apis mellifera)

    Mariapia Viola-Magni , Samuela Cataldi

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 43-48
    Received: 7 August 2014
    Accepted: 14 August 2014
    Published: 2 September 2014
    DOI: 10.11648/j.ajbio.s.2014020601.18
    Downloads:
    Views:
    Abstract: Homeobox genes are present in the genome of the honeybee Apis mellifera and their expression has been studied principally during embryonic development. The aim of this research was to evaluate expression of three key Hox genes from the larval period to the adult. The expression of honeybee GB51301, Ant and Ubx were examined in 24 and 72 hrs of larv... Show More
  • Patent Foramen Ovale is Associated with an Increased NAFLD Risk for Health of Young Men

    Erkan Kibrisli , Sinan Işcen , Salim Ozenc , Adem Parlak

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 35-38
    Received: 13 August 2014
    Accepted: 19 August 2014
    Published: 24 August 2014
    DOI: 10.11648/j.ajbio.s.2014020601.16
    Downloads:
    Views:
    Abstract: Between March 2012 and July 2013, 1000 asymptomatic young military male underwent hepatic ultrasonography and echocardiography at Medical Check-up Center for general young health screening. Blood biochemistry, arterial blood pressure and anthropometric measurements were studied. All analyses were performed using the statistical package SPSS 15.0, w... Show More
  • Chemical Synthesis, Spectral Characterization and Antimicrobial Studies on Complexes of Ni(II), Cu(II) and Zn(II) with N, N-di (o-hydroxybenzenoylmethylene) Ethylenediamine

    Ali Mohammed Yimer

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 22-34
    Received: 30 June 2014
    Accepted: 14 July 2014
    Published: 20 August 2014
    DOI: 10.11648/j.ajbio.s.2014020601.15
    Downloads:
    Views:
    Abstract: The Schiff’s base ligands and their complexes with Ni(II), Cu(II) and Zn(II) were synthesized and characterized by elemental analysis molar conductivity, infrared and ultraviolet-visible spectroscopy and magnetic susceptibility measurements. The ligands, ethylenedianil of o-hydroxyphenylglyoxal, C18H16N2O4, have been synthesized by condensation of ... Show More
  • Morphological and Genetic Variation of Thrips parvispinus (Thysanoptera: Thripidae) in Chili Plantation (Capsicum annuum L.) in the Lowland and Highland of Jambi Province, Indonesia

    Asni Johari , Siti Herlinda , Yulia Pujiastuti , Chandra Irsan , Dewi Sartiami

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 17-21
    Received: 30 May 2014
    Accepted: 18 July 2014
    Published: 8 August 2014
    DOI: 10.11648/j.ajbio.s.2014020601.14
    Downloads:
    Views:
    Abstract: Thrips parvispinus Karny (Thysanoptera: Thripidae) are dangerous pests for chili (Capsicum annuum L.). Thrips can be found in lowland to highland. The damage caused by thrips can reach 60% and this damage will be greater if the thrips also be vectors of plant virus diseases. The research aims to analyze morphological and genetic variation of T. par... Show More
  • Study of Enzymatic Hydrolysis of Bacterial Nanocellulose

    Michael Ioelovich

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 13-16
    Received: 28 June 2014
    Accepted: 10 July 2014
    Published: 13 July 2014
    DOI: 10.11648/j.ajbio.s.2014020601.13
    Downloads:
    Views:
    Abstract: Bacterial nanocellulose is a subject of extensive research due to its promising potential applications in medicine, veterinary and cosmetics. In this paper, effect of structural characteristics on enzymatic hydrolysis of bacterial nanocellulose (BNC) and microcrystalline cellulose (MCC) has been studied. Despite the similar degree of crystallinity ... Show More
  • Structure and Physicochemical Properties of Nitrogenated Derivatives of Cellulose

    Michael Ioelovich

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 6-12
    Received: 28 June 2014
    Accepted: 10 July 2014
    Published: 13 July 2014
    DOI: 10.11648/j.ajbio.s.2014020601.12
    Downloads:
    Views:
    Abstract: Nitrogenated derivatives of cellulose, and namely chitin and chitosan, are of commercial interest because of their antibacterial activity, biocompatibility, biodegradability and sorption ability. Structure and some physicochemical properties of these derivatives have been studied by methods of wide-angle X-ray scattering (WAXS), microcalorimetry an... Show More
  • The Study of Comparative Analgesic Activity of Lidocaine and Ropivacaine on Albino Rats

    Thota. Madhu Chaithanya , MundllaMudi. Prasad Naidu

    Issue: Volume 2, Issue 6-1, November 2014
    Pages: 1-5
    Received: 5 June 2014
    Accepted: 4 July 2014
    Published: 13 July 2014
    DOI: 10.11648/j.ajbio.s.2014020601.11
    Downloads:
    Views:
    Abstract: Analgesics are the drugs which possess significant pain relieving properties by acting on the CNS or peripheral pain receptors without significantly affecting consciousness. Lidocaine and Ropivacaine are well studied individually; but there are conflicting reports of the comparison of actions between these two drugs both in experimental and clinica... Show More